Maintaining crew members' health is a top priority in human spaceflight activities. Recent advances in technology and telemedicine aim to reduce the distance between the crew and the medical team with the help of novel monitoring and diagnostic devices. In particular, the field of imaging is dominated by ultrasound, a non-invasive and versatile modality that enables a wide range of examinations. The activity covers the development of a multimodal crew monitoring system for training, in-flight, and readaptation, and also to collect this data in a centralized manner for future machine-based processing, called AMCE (Astronaut Medical Control Equipment). REMRED Ltd. is the developer of the equipment to be provided for the Semmelweis University of Budapest in the frame of the Hungarian Research Astronaut Programme (HUNOR).